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Archive for the ‘Uncategorized’ Category

Personal freedom of genome access vs. innovation-crushing government regulation

Posted in Uncategorized, tagged , , on July 23, 2010 | Leave a Comment »

Image via Wikipedia Pointer to Daniel MacArthur’s (Genomes Unzipped) post on the recent political grandstanding in consumer genetics. This blog is more genomes, brains, social entrepreneurship and health 2.0 – than politics.   Hopefully the political phase will soon pass and some sensible regulations will preserve the right of consumers to access their genomes, while protecting [...]

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Inheritance of epigenetic change?

Posted in Uncategorized, tagged , , , , on April 27, 2010 | 1 Comment »

Image via Wikipedia pointer to the NOVA program on epigenetics “Ghost in Your Genes” (YouTube link here).  Fantastic footage.  Great intro to epigenetics and so-called trans-generational effects and the inheritance of epigenetic marks – which, in some cases – are left by adverse or stressful experience.  A weird, wild, game-changing concept indeed – that my [...]

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echoblog: Dad, Mom ‘n kids go all-in for full sequence

Posted in Uncategorized, tagged , , , , on April 22, 2010 | Leave a Comment »

Image via Wikipedia just a pointer to: Genetic Future’s pointer to the recent article, “Family become first to have DNA sequenced for non-medical reasons“.    The father suggests, “it will be ethically improper if you don’t have your children sequenced“. Early days.

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tiny lego brain

Posted in Uncategorized, tagged , on April 18, 2010 | Leave a Comment »

“Hey Dad, look at the little bwain!”  (my 4 y.o.)

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Don’t ask what the genes for Prader-Willi syndrome do, ask where

Posted in Uncategorized, tagged , , , , , , , , , , on April 8, 2010 | Leave a Comment »

Image by Si1very via Flickr In an earlier post on Williams Syndrome, we delved into the notion that sometimes a genetic variant can lead to enhanced function – such as certain social behaviors in the case of WS.  A mechanism that is thought to underlie this phenomenon has to do with the way in which [...]

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First ever replication of a GxE in psychiatric genetics

Posted in CRHR1, Uncategorized, tagged , , , , , , , , , , on April 6, 2010 | Leave a Comment »

Image via Wikipedia According to the authors of  “Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension“  [PMID: 19736354], theirs is “the first instance of Genes x Environment research that stress has been ascertained by more than 1 study using the same instrument“.  The gene they [...]

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Bigger genetic studies, more missing heritability

Posted in Chromosome structural variants, Intronic or repetitive sequences, Uncategorized, tagged , , , , , , , , , , , , , , , on April 5, 2010 | 1 Comment »

Twin studies have long suggested that genetic variation is a part of healthy and disordered mental life.  The problem however – some 10 years now since the full genome sequence era began – has been finding the actual genes that account for this heritability. It sounds simple on paper – just collect lots of folks [...]

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Wanted

Posted in Uncategorized, tagged , on April 3, 2010 | Leave a Comment »

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Brains in the genes

Posted in Uncategorized, tagged , on March 30, 2010 | Leave a Comment »

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Remember when

Posted in Uncategorized, tagged , on March 30, 2010 | Leave a Comment »

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homunculi

Posted in Uncategorized, tagged , on March 20, 2010 | 2 Comments »

When making our jello-brain, we entombed a tiny lego man in the frontal lobe to capture the idea of an homunculus, or tiny human.  Neuroscientists try and avoid implicating this little guy when positing mechanisms of self-control and decision making.  Here, my son Ben decided to liberate our lego homunculus whilst eating the left parietal [...]

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brain du jour

Posted in Uncategorized, tagged , on March 20, 2010 | Leave a Comment »

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Interview with Professor Chandan Vaidya, Georgetown University

Posted in Uncategorized, tagged , , , , , on March 11, 2010 | Leave a Comment »

Image via Wikipedia It was a delight to speak with Professor Vaidya this morning on her recent article, Neural response to working memory load varies by dopamine transporter genotype in children.  An understanding of how a single genetic variant can relate to brain function, behavior and clinical intervention involves the synthesis of a great many [...]

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genomachino

Posted in Uncategorized, tagged , on March 6, 2010 | Leave a Comment »

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Genetic road signs for super-size coffee SUV drivers

Posted in ADORA2A, DRD2, Uncategorized, tagged , , , , , , , , , , , , , , , , , on March 4, 2010 | Leave a Comment »

If you’re a coffee drinker, you may have noticed the new super-sized portions available at Starbucks.  On this note, it may be worth noting that caffeine is a potent psychoactive substance of which – too much – can turn your buzz into a full-blown panic disorder.  The Diagnostic and Statistical Manual for psychiatry outlines a [...]

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Francis Freud

Posted in Uncategorized, tagged , on February 25, 2010 | Leave a Comment »

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-ome rave

Posted in Uncategorized, tagged , on February 22, 2010 | Leave a Comment »

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SOD2

Posted in Uncategorized, tagged , on February 19, 2010 | Leave a Comment »

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ear wax gene

Posted in Uncategorized, tagged , on February 18, 2010 | Leave a Comment »

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DNA is not destiny meme

Posted in Uncategorized, tagged , on February 17, 2010 | Leave a Comment »

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