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a loose take on TNF-alpha at the cross roads of immunity, obsession & heart function (real science here & here).

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X-mas shopping

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when you realize that the genetic risk of that allele you carry was calculated using a small population from south-western-upper-middle-eurasia-stan … and doesn’t really apply to your individual situation.

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thank you ugly renaissance babies.

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Biocomicals!

Check out Biocomicals!

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Perhaps just a little bit.  One Law Professor’s experience. “As it happens, … It turned out that I had a genetic variant that implied a moderately increased risk of meningioma, the second most common type of brain tumor. The information came a little late to be useful. Last summer, … found me half conscious on [...]

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The article here:

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We all have a story.  You know, the narrative of you … your life, its twists and turns … the person you are inside, the person you want(ed) to be … the special, unique person that you are.  Your story is something you naturally think about … a lot.  Is this who I am? … [...]

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Mitochondrial damage is associated with premature aging in the body and related disorders such as Parkinson’s Disease in the brain.  If you want to grow old and healthy … be nice to your mitochondria … eat healthy foods and exercise. When mitochondria are damaged, cells can use proteolysis to clean them out, but when this [...]

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Hilarious!!!!!! Check it out here.

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Dr. Tal Yarkoni: “Functional MRI in Health Psychology and beyond: A call for caution“ In practice, the modal fMRI sample size of 15 – 20 subjects often provides little power to detect anything but very large effects (Yarkoni, 2009). For example, a one-sample t test performed on 20 subjects at a statistical threshold of p [...]

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You mean these types of executives?  No … well, sort of, maybe.  Some people can control their thoughts and actions better than others. Individuals vary widely in their abilities to control their own thoughts and actions. Some people seem ruled by impulses, while others manage successfully to regulate their behaviors. From the perspective of cognitive [...]

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… but you knew that already.  Here’s an example of how a phenomenon known as exon shufflin’ can lead to evolutionary diversity (here involving SNAP25‘s exon 5a variant for early brain development while the exon 5b variant is used later in development) .  Perhaps we owe our awesome, ahem, “higher” cognitive abilities to this ancient [...]

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Some call it “phantom heritability” while others call it “dark matter” … whatever … genes are definitely not “beans in a bag” that independently add up to influence development.  They interact in complex bio-physical-3D-proteo-ribonucleic-tertiary-etc.-etc. ways. “Ultimately,” they concluded, “the most important goal for biomedical research is not explaining heritability — that is, predicting personalized patient [...]

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[article here]

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hacked from animals talking in all caps

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Here’s an excerpt from William Vollmann’s book Poor People … of an exchange between two men … one, a passerby, and the other, homeless “young, bearded, well-clad, his his bluejean legs sewn into pockets around his stumps“. He expressed through his noninsistence my right not to give him anything, and the little that I did [...]

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Check out the Interpretome! developed by students and staff at Stanford University. – I have 17 European alleles and 3 East Asian alleles … the genetic proof is in … white boys can’t jump. – I have 17 out of 32 Type 2 Diabetes risk alleles … put down those carbs now … and 19 [...]

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Come to think of it, I was never very, um, choosy, back in my wanton late teens and early 20′s … apparently, it runs in the family.  News blurb.

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