Image via Wikipedia pointer to the NOVA program on epigenetics “Ghost in Your Genes” (YouTube link here). Fantastic footage. Great intro to epigenetics and so-called trans-generational effects and the inheritance of epigenetic marks – which, in some cases – are left by adverse or stressful experience. A weird, wild, game-changing concept indeed – that my [...]
Posts Tagged ‘Add new tag’
Inheritance of epigenetic change?
Posted in Uncategorized, tagged Add new tag, Biology, Epigenetics, Gene expression, NOVA on April 27, 2010 | 1 Comment »
First ever replication of a GxE in psychiatric genetics
Posted in CRHR1, Uncategorized, tagged Add new tag, Depression, Development, Emotion, Genetics, Hypothalamic–pituitary–adrenal axis, Major depressive disorder, Mental disorder, Mental health, Single-nucleotide polymorphism, Stress on April 6, 2010 | Leave a Comment »
Image via Wikipedia According to the authors of “Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension“ [PMID: 19736354], theirs is “the first instance of Genes x Environment research that stress has been ascertained by more than 1 study using the same instrument“. The gene they [...]
Bigger genetic studies, more missing heritability
Posted in Chromosome structural variants, Intronic or repetitive sequences, Uncategorized, tagged Add new tag, Biology, bipolardisorder, Copy number variation, Depression, DNA, Gene, Genetic testing, Genetic variation, Genetics, Genome-wide association study, Mental disorder, Mental health, Single-nucleotide polymorphism, Twin, Twin study on April 5, 2010 | 1 Comment »
Twin studies have long suggested that genetic variation is a part of healthy and disordered mental life. The problem however – some 10 years now since the full genome sequence era began – has been finding the actual genes that account for this heritability. It sounds simple on paper – just collect lots of folks [...]
Photoperiod sensitive humans bloom much like spring flowers
Posted in Suprachiasmatic nucleus, tagged 23andMe, Add new tag, Biology, bipolardisorder, Brain, Circadian rhythm, CLOCK, Depression, DNA, Mental health, Mood disorder, Seasonal affective disorder on March 17, 2010 | Leave a Comment »
Image by noahg. via Flickr If you’ve started to notice the arrival of spring blossoms, you may have wondered, “how do the blossoms know when its spring?“ Well, it turns out that its not the temperature, but rather, that plants sense the length of the day-light cycle in order to synchronize their own life cycles [...]
rs2132683, rs713155 and white matter near the left posterior lateral ventricle emerge from 14 billion statistical tests (vGWAS)
Posted in Frontal cortex, Lateral ventricle, Temporal lobe, White matter, tagged 23andMe, Add new tag, Brain, brain structure, Development, Frontal lobe, Genetics, Genome-wide association study, GWAS, Neuroimaging, Statistical hypothesis testing, Statistics, Temporal lobe, White matter on March 12, 2010 | 1 Comment »
An historic find has occurred in the quest (gold-rush, if you will) to link genome variation with brain structure-function variation. This is the publication of the very first genome-wide (GWAS) analysis of individual voxels (voxels are akin to pixels in a photograph, but are rather 3D cubes of brain-image-space about 1mm on each side) of [...]
Interview with Professor Chandan Vaidya, Georgetown University
Posted in Uncategorized, tagged Add new tag, Dopamine transporter, Georgetown University, Podcast, Professor, Psychology on March 11, 2010 | Leave a Comment »
Image via Wikipedia It was a delight to speak with Professor Vaidya this morning on her recent article, Neural response to working memory load varies by dopamine transporter genotype in children. An understanding of how a single genetic variant can relate to brain function, behavior and clinical intervention involves the synthesis of a great many [...]
rs35753505 C-alleles make de l’Art Brut of the brain
Posted in Fusiform gyrus, Middle frontal gyrus, middle occipital gyrus, NRG1, tagged 23andMe, Add new tag, Art, Brain, Cognition, DNA, Frontal lobe, Functional magnetic resonance imaging, Fusiform gyrus, Memory, Mental disorder, Mental health, Outsider art, Painting on March 10, 2010 | Leave a Comment »
According to wikipedia, “Jean Philippe Arthur Dubuffet (July 31, 1901 – May 12, 1985) was one of the most famous French painters and sculptors of the second half of the 20th century.” “He coined the term Art Brut (meaning “raw art,” often times referred to as ‘outsider art’) for art produced by non-professionals working outside [...]
A look inside brains that carry (my) genetic risk for autism
Posted in Cerebellum, CNTNAP2, Frontal cortex, Frontal pole, Fusiform gyrus, Rostral fronto-occipital fasciculus, Thalamus, White matter, tagged 23andMe, Add new tag, autism, Autism spectrum, Brain, Development, Frontal lobe, Functional magnetic resonance imaging, Genetic testing, Genetics, Grey matter, Health, Mental disorder, Mental health, Neural development, Neurodevelopmental, synaptogenesis, White matter on March 5, 2010 | Leave a Comment »
Image via Wikipedia The A-to-T SNP rs7794745 in the CNTNAP2 gene was found to be associated with increased risk of autism (see Arking et al., 2008). Specifically, the TT genotype, found in about 15% of individuals, increases these folks’ risk by about 1.2-1.7-fold. Sure enough, when I checked my 23andMe profile, I found that I’m [...]
Coping with the shifting sands of development one grain at a time
Posted in SAPAP3, Striatum, tagged Add new tag, Adolescence, Brain, Chemical synapse, Development, Mental disorder, NMDA, NMDA receptor, Obsessive–compulsive disorder, Walter Dean Myers, Young Landlords on February 22, 2010 | Leave a Comment »
Image by mbrownstone via Flickr Walter Dean Myers, an author of The Young Landlords and many other classic coming of age novels once remarked, “The special place of the young adult novel should be in its ability to address the needs of the reader to understand his or her relationships with the world, with each [...]
C.H. Waddington provides conceptual framework for shifting influences of genes and environment in the development of mind
Posted in Uncategorized, tagged Add new tag, Brain, Cognition, cognitive development, Development, evolution, Genetics, Human behavior, Intelligence, Mutation, Population genetics, Psychology, Twin, University of Edinburgh on January 12, 2010 | Leave a Comment »
Just a pointer to onetime University of Edinburgh Professor C.H. Waddington’s 1972 Gifford Lecture on framing the genes vs. environment debate of human behavior. Although Waddington is famous for his work on population genetics and evolutionary change over time, several of his concepts are experiencing some resurgence in the neuroimaging and psychological development literatures these [...]
“sintinaptoo” is a nonword that makes it hard to read nonwords
Posted in CNTNAP2, FOXP2, Myelin, Superior temporal cortex, tagged 23andMe, Add new tag, Development, evolution, language on November 7, 2008 | Leave a Comment »
Image by lintmachine via Flickr Like “Joe the Plumber” (whose real name is Samuel), CNTNAP2 (whose real name is CASPR2) has achieved a bit of fame lately. While recently appearing almost everywhere (here, here, here) except FOX News, CNTNAP2 (not Joe the Plumber) is apparently a transcriptional target of the infamous FOXP2 “language gene” – [...]
Retweetin’
- My genome is the Influenza Virus' stanky bitch - “SNPs in proximity to two genes related to syndromes where... tmblr.co/ZVTWNvMYj9J7 3 hours ago
- RT @Margaretshoop: I love people shutting up even more than I love people 4 hours ago
- Hey, a system that creates new expectations every second of its existence ... ain't gonna sit still for... tmblr.co/ZVTWNvMYA456 7 hours ago
- Link: tmblr.co/ZVTWNvMY8kku 7 hours ago
- Photo: tmblr.co/ZVTWNvMU4JS5 1 day ago
-
Remarks
James Rayment on The vagus nerve as a living Ku… thesingernurse on DRD4 and gene-twitter interact… Dr Robert Peers on Are individual differences in … dendrite on Genomic solutions for really b… Neural Outlet.. on Genomic solutions for really b… cariaso on Are there genes for my favorit… dreambot on The vagus nerve as a living Ku… Aubrey de Grey Gets … on Movie star SIRT1 makes for a g… Kala Pierson on What is the sound of Aum? Jeremy Peirce on What is the sound of Aum? Alexei Morozov on red purple blue dendrite on Genetic testing across the US … dendrite on Genetic testing across the US … dendrite on Genetic testing across the US … rh on Genetic testing across the US … -
Blog Stats
- 75,536 clickitas
Posting since April 2007
Who are you? & thanks for your interest!
General topics
Specific Items
- 5HTT
- ABCB1
- acetylcholine
- Actin
- ACTN3
- ADH1C
- ADORA2A
- ADRA2A
- AMPA receptor
- Amygdala
- Angular gyrus
- ANK3
- APOE
- ARHGAP18
- ASIC1a
- ASPM
- ATXN1
- AVPR1a
- BAF53b
- Basal Ganglia
- BDNF
- CABYR
- CACNA1C
- CACNA2D1
- Caudate nucleus
- CB1 receptor
- CDC34
- CDH13
- Cell adhesion molecules
- Cerebellum
- CHAT
- CHRM3
- CHRNA4
- CHRNA7
- Chromosome structural variants
- Cingulate cortex
- clinical trial
- CNTNAP2
- Collateral sulcus
- COMT
- Corpus callosum
- COX1
- CREB
- CRHR1
- DARPP32
- DAT
- default network
- DISC1
- DLPFC
- DNMT
- Dopamine
- DRD2
- DRD4
- DTNBP1
- DYRK1A
- EDA2R
- EGR1
- Estrogen
- evolution
- FGF20
- FMR1
- FNBP1L
- FOXA2
- FOXP2
- Frontal cortex
- Frontal pole
- Fusiform gyrus
- G-protein
- GABA
- GABRA2
- GATA4
- Glucocorticoid receptor
- Glutamate
- GPR6
- GRIA3
- GRIK2
- GTPase
- HDACs
- Hippocampus
- HOXB8
- HTR2A
- Hypothalamus
- immunity
- Inferior frontal gyrus
- Insula
- Intronic or repetitive sequences
- Kalirin
- KCNA2
- KCNH2
- KCNIP3
- KCNJ6
- Kinesin
- Lateral septum
- Lateral ventricle
- LDB1
- Leptin
- LIMK1
- Locus coeruleus
- MAOA
- MAPK
- MCPH1
- MCR1-4
- MDGA2
- MECP2
- meditation
- metabolism
- MHC loci
- microRNA
- Middle frontal gyrus
- middle occipital gyrus
- Middle temporal gyrus
- Mindfulness
- MKP-1
- Motor cortex
- Myelin
- Neural crest
- NEUROG1
- NLGN3/4
- Noradrenaline
- NPSR1
- NRG1
- NRXB1
- NTRK2
- Nucleus accumbens
- NURR1
- Olfactory bulb
- OPRM1
- Orbitofrontal cortex
- OTR
- OXTR
- Parahippocampal gyrus
- Parasympathetic NS
- Parietal cortex
- PARP-1
- PCLO
- PINK1
- Posterior parietal cortex
- PSD95
- Putamen
- quantum physics
- RARB
- RGS2
- RGS4
- Rho GTPase
- RLN
- Rostral fronto-occipital fasciculus
- RSRC1
- SAPAP3
- self-awareness
- SEMA(1-7)
- SETDB1
- SEZ6
- SIRT1
- SLC1A1
- SLITRK1
- SNAP25
- SNORD115
- SNRPN
- SOD2
- Somatosensory cortex
- SRPX2
- Stria terminalis
- Striatum
- Substantia nigra
- Subthalamic nucleus
- Superior temporal cortex
- Suprachiasmatic nucleus
- Supramarginal gyrus
- SWI/SNF
- Sylvian fissure
- Telomere
- Temporal lobe
- TGF-alpha
- TH
- Thalamus
- Thap1
- THBS1
- THBS2
- TNF-alpha
- Torsin A
- TPH2
- UBE3A
- UGT2B17
- Uncategorized
- Vagus
- VEGF
- Ventral tegmental area
- VGF
- Visual cortex
- White matter
- Yoga and Meditation
- ZNF804A
