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Posts Tagged ‘Personalized medicine’

Image by Getty Images via Daylife While often the object of scorn from its capitalistic southern neighbor, the Canada Foundation for Innovation has just awarded Dr. David Kennedy a large research grant to deploy both neuroimaging and genetic markers in the development of personalised treatment for schizophrenia – through a program dubbed “neuroIMAGENE“.  Dr. Kennedy [...]

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Image by TW Collins via Flickr Was bummed to hear Nick Haymenn say (download & listen to minute 10 on this Bloomberg News podcast) that GE healthcare has abandoned its molecular & imaging diagnostics program aimed at early detection and intervention. Crap, that sets things back quite a bit across the medical universe I suspect.

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Image by greeley via Flickr A great article (here in the NYTimes magazine) on one psychologist’s reaction to his genome and the new consumer genomics.

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Image via Wikipedia Doctor David Ledbetter gives an eloquent editorial overview in his piece, “Cytogenetic Technology: Genotype and Phenotype” [doi: 10.1056/NEJMe0806570] on the renaissance underway in the field of medical cytogenetics. The use of high density arrays for genome-wide copy number variation has identified a slew of new sites showing recurrent microdeletion that are reliably [...]

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Just saw this on engadget … fun and useful – just like chumby but with a medical twist. Who knows, it may someday make housecalls (see link below).Related articles by Zemanta Hacker goes bananas, creates robotic Chumby driving machine

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Image via CrunchBase, source unknown Just re-posting from Gizmodo … this looks like a positive step … a medical chumby.

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The selection and dosing of medication in psychiatry is far from scientific – even though a great deal of hard science goes into the preclinical design and clinical development. One reason, among many, has to do with the so-called ‘inverted-U-shaped’ relationship between the dose of a psychoactive compound and an individuals’ performance. Some folks show [...]

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Image via Wikipedia Recent meta-analytical research, “Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy” (N Engl J Med 2008;358:252-60) reveals that while 94% of published antidepressant drug trials show positive findings, only 51% of all such (published and unpublished) trials show positive effects (with a range of effect sizes from 11-69%). This [...]

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Image by dbking via Flickr Amidst the excitement of new personalized genome services, the Economist reports on fraudsters found peddling ‘personalized supplements’ based on bogus genetic testing results. This is an extreme, tragicomic example to be sure, but highlights some of the issues that can arise when confronting one’s genetic blueprint. A recent paper by [...]

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Image via Wikipedia Uhl and colleagues present a genome-wide search for SNPs that distinguish smokers (nicotine dependence) – and perhaps more importantly – successful smoking quitters, in their recent article in the free and open-access journal BioMed Central. As pointed out in the article, this work is a step closer to personalized “efforts to match [...]

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Image via Wikipedia I’m not sure how they will compete with the open community effort of the Personal Genome Project, but they do have a very slick commercial. Check out Navigenics and you’ll feel your saliva start to flow !

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Image via Wikipedia Christopher Rowland gives a great perspective on the new venture fund at the Harvard Partners Healthcare system. If you want a peek at the future of personalized medicine, check out the Partners Center for Genetics and Genomics – where basic research is seamlessly integrated with clinical care. I attended their first annual [...]

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