My white matter needs epigenetic change encoded by the genome

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My white matter needs epigenetic change encoded by the genome

November 26, 2010 by dendrite

: Image by Myelin Repair Foundation via Flickr

from Ye et al., 2009:

HDAC1/2 genes encode proteins that modify the epigenome (make it less accessible for gene expression).

When HDAC1/2 functions around the HES5 and ID2/4 (repressors of white matter development) genes, the epigenetic changes (less acetylation of chromatin) helps to repress the repressors.

This type of epigenetic repression of gene expression (genes that repress white matter development) is essential for white matter development.

Posted in HDACs | Tagged Central nervous system, Development, Epigenetics, Gene expression, White matter | 3 Comments

3 Responses

on December 3, 2010 at 4:35 pm | Reply Lamarck, Jean-Baptiste Pierre Antoine de Monet, Chevalier de « Earthpages.ca

[…] My white matter needs epigenetic change encoded by the genome (genes2brains2mind2me.com) […]
on February 1, 2011 at 1:47 pm | Reply A Picture is Worth a 1,000 Words « The Epigenetics Project Blog

[…] My white matter needs epigenetic change encoded by the genome (genes2brains2mind2me.com) […]
on February 3, 2011 at 12:54 pm | Reply Next Post « The Epigenetics Project Blog

[…] My white matter needs epigenetic change encoded by the genome (genes2brains2mind2me.com) […]

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Genes 2 Brains 2 Mind 2 Me

genome-guided introspection (most recently while living in the web3 metaverse)

My white matter needs epigenetic change encoded by the genome

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